SPARC-IBD
PIs: James D. Lewis, MD, MSCE and Meenakshi Bewtra, MD, PhD, MPH
For potential eligibility and interested patients, contact: i3study@pennmedicine.upenn.edu
For potential eligibility and interested patients, contact: i3study@pennmedicine.upenn.edu
The overarching goal of the Study of the Prospective Research Cohort with Inflammatory Bowel Disease (SPARC IBD) is to create a longitudinally followed, well phenotyped cohort of patients with IBD who have linked clinical data, self-reported outcome data, and biosamples that can be used for clinical and translational research.
SPARC IBD—Study of a Prospective Adult Research Cohort with IBD—is a multicentered longitudinal study of adult IBD patients, which will collect and link clinical data, patient-reported outcome data, and serial biosamples through the course of the patients' disease. Data and samples will then be used for basic, clinical, and translational research with the goal of finding predictors of response to therapy and predictors of relapse that will lead to precision medicine strategies and new therapeutic targets that will improve the quality of life of patients with IBD.
When fully enrolled, SPARC will follow 7,000 well-characterized (phenotyped) adult patients, integrating their clinical data and self-reported outcome data and collecting serial biosamples over the course of their disease.
Samples can be used for basic, clinical, and translational research:
When fully enrolled, SPARC will follow 7,000 well-characterized (phenotyped) adult patients, integrating their clinical data and self-reported outcome data and collecting serial biosamples over the course of their disease.
Samples can be used for basic, clinical, and translational research:
- Comparative effectiveness research
- Hypothesis/evidence generation
- Drug targets and biomarkers discovery
Inclusion Criteria
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Exclusion Criteria
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• Individuals aged 18 years or older, comprising adult patients • Afflicted with Inflammatory Bowel Disease (IBD) encompassing Crohn's Disease (CD), Ulcerative Colitis (UC), or IBD unspecified (previously known as indeterminate colitis) • Patients under the care of any of the collaborating sites • Proficiency in spoken and written English is required for participants. |
•Inability to provide informed consent
•Patients presenting for a one time consultation •Students or employees who are directly supervised by one of the investigators |
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