IBD Immunology Initiative
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    • Meenakshi Bewtra
    • John Wherry
    • Nicole Belle
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    • Marykate Fulton
    • Baron Chen
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PUBLICATIONS AND AWARDS

Awards won by members of our research team:

https://almanac.upenn.edu/articles/e.-john-wherry-innovation-in-collaboration-award
​

Dr. Bewtra won the Doctors of America Founders Award for Excellence in Advocacy (2022)
​

' Our team has published some of our findings:

IBD Patients' Willingness to Accept Medication Risk to Avoid Future Disease Relapse.
Bewtra M, Fairchild AO, Gilroy E, Leiman DA, Kerner C, Johnson FR, Lewis JD.
Am J Gastroenterol. 2015 Dec;110(12):1675-81. doi: 10.1038/ajg.2015.321. Epub 2015 Oct 20.
PMID:26482859

An optimized patient-reported ulcerative colitis disease activity measure derived from the Mayo score and the simple clinical colitis activity index.
Bewtra M, Brensinger CM, Tomov VT, Hoang TB, Sokach CE, Siegel CA, Lewis JD.
Inflamm Bowel Dis. 2014 Jun;20(6):1070-8. doi: 10.1097/MIB.0000000000000053.
PMID:24810138

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CG, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M, Snyder A, Giacomin PR, Joyce KL, Hoang TB, Bewtra M, Brodsky IE, Sonnenberg GF, Bushman FD, Won KJ, Lazar MA, Artis D.
Nature. 2013 Dec 5;504(7478):153-7. doi: 10.1038/nature12687. Epub 2013 Nov 3.
PMID:24185009

Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche
Tomov VT, Palko O, Lau CW, Pattekar A, Sun Y, Tacheva R, Bengsch B, Manne S, Cosma GL, Eisenlohr LC, Nice TJ, Virgin HW, Wherry EJ.
2017 Oct17;47(4):723-738.e5. doi: 10.1016/j.immuni.2017.09.017. Epub 2017 Oct 11.
PMID: 29031786
 
Gut microbiota and IBD: causation or correlation?
Ni J, Wu GD, Albenberg L, Tomov VT.
Nat Rev Gastroenterol Hepatol. 2017 Oct;14(10):573-584. doi: 10.1038/nrgastro.2017.88. Epub 2017 Jul 19.
PMID: 28743984
 
High-dimensional immune phenotyping and transcriptional analyses reveal robust recovery of viable human immune and epithelial cells from frozen gastrointestinal tissue.
Konnikova L, Boschetti G, Rahman A, Mitsialis V, Lord J, Richmond C, Tomov VT, Gordon W, Jelinsky S, Canavan J, Liss A, Wall S, Field M, Zhou F, Goldsmith JD, Bewtra M, Breault DT, Merad M, Snapper SB.
Mucosal Immunol. 2018. Nov;11(6):1684-1693. doi: 10.1038/s41385-018-0047-y. Epub 2018 Aug 15.
PMID: 30111863

The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium
Monica T. Jimenez, Megan L. Clark, Jasmine M. Wright, Michaël F. Michieletto, Suying Liu, Isabel Erickson, Lenka Dohnalova, Giulia T. Uhr, John Tello-Cajiao, Leonel Joannas, Adam Williams, Nicola Gagliani, Meenakshi Bewtra,Vesselin T. Tomov,Christoph A. Thaiss,Jorge Henao-Mejia 
J Exp Med 2022 Dec 5;219(12):e20212278. doi: 10.1084/jem.20212278. Epub 2022 Sep 8.
PMID: 36074090

High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature
A-M Globig, A V Hipp, P Otto-Mora, M Heeg, L S Mayer, S Ehl, H Schwacha, M Bewtra, V Tomov, R Thimme, P Hasselblatt, B Bengsch 
Nat Commun. 2022 Jun 27;13(1):3688.doi: 10.1038/s41467-022-31229-z.
​PMID: 35760777
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Copyright © 2020
  • Home
  • About
  • Meet the I3 Team
    • Meenakshi Bewtra
    • John Wherry
    • Nicole Belle
    • Robert Kilpatrick
    • Marykate Fulton
    • Baron Chen
  • What is IBD?
  • How Can You Contribute?
  • Associated Studies
  • Publications and Awards
  • In the News
  • Current Events
  • FAQ
  • Contact
  • Comments, Questions Concerns?